Gangadhar, Daboo, Raja and Mukherjee are all patients of a mental hospital in Khandala, with different mental problems. They are under the care of Dr. Sonali Sanyal, who seeks permission of her senior to take them to Mumbai to watch a cricket match. Once there, Dr. Sonali is kidnapped by a police inspector, DCP Shrivastav, who is acting at her husband’s behest! Somehow, the four patients learn that Dr. Sonali’s own husband and the police officer are behind Dr. Sonali’s kidnapping. While their mission is twofold – to trace Dr. Sonali and to bring the criminals to book – DCP Shrivastav and Sanyal feel threatened by the four mad men because they know the truth and, therefore, want to eliminate them. The foursome seeks the help of Shikha, who works in a television channel, to expose the real men and their deeds.